Skincare is more than just a routine—it’s a way to care for yourself and boost your confidence. With so many brands out there, finding the right one can feel overwhelming. If you’re looking for high-quality, effective, and innovative skincare, American brands are leading the way. From affordable drugstore staples to luxurious splurges, these brands offer something for every skin type and concern. Here’s our list of the top 10 American skincare brands you need to try in 2025, packed with products that deliver real results.

Why Choose American Skincare Brands?
American skincare brands are known for their cutting-edge formulas, science-backed ingredients, and commitment to quality. Many prioritize clean beauty, sustainability, and inclusivity, catering to diverse skin tones and concerns. Whether you’re battling acne, dryness, or signs of aging, these brands have you covered. Plus, they’re often backed by dermatologists, estheticians, and glowing customer reviews, making them a trusted choice for skincare lovers.
Let’s dive into the 10 best American skincare brands that deserve a spot in your routine.
1. CeraVe
CeraVe is a household name for a reason. Founded in 2005, this brand is loved for its affordable, dermatologist-developed products that focus on repairing the skin’s natural barrier. Their hero ingredients—ceramides, hyaluronic acid, and niacinamide—make their cleansers, moisturizers, and sunscreens a go-to for sensitive skin. In 2024, CeraVe was ranked the top skincare brand among Gen Z in the U.S., with 37% of respondents naming it their favorite.
Must-Try Product: CeraVe Hydrating Facial Cleanser ($11.38) – gentle, non-drying, and perfect for daily use.
2. The Ordinary
Since its launch in 2016, The Ordinary has revolutionized skincare with its no-nonsense, affordable approach. Known for transparent ingredient lists and clinical formulations, this brand makes high-performance serums and treatments accessible to all. Their Niacinamide 10% + Zinc 1% Serum is a fan favorite for tackling oiliness and breakouts.
Must-Try Product: The Ordinary Hyaluronic Acid 2% + B5 ($8.90) – a lightweight serum for intense hydration.
3. Drunk Elephant
Drunk Elephant is a clean beauty powerhouse, offering cruelty-free products free of harsh chemicals. Founded by Tiffany Masterson, the brand focuses on biocompatible ingredients that work with your skin. Their T.L.C. Sukari Babyfacial Mask is a cult classic, delivering a spa-like exfoliation at home.
Must-Try Product: Drunk Elephant C-Firma Vitamin C Day Serum ($80) – brightens and firms with a potent dose of vitamin C.

4. Glossier
Glossier, born from a beauty blog, is all about enhancing your natural glow. Their minimalist, skincare-first approach has won over millennials and Gen Z alike. Products like Balm Dotcom and Milky Jelly Cleanser are staples for those who love simple, effective routines. Everything is made in the USA, with a focus on fun, user-friendly packaging.
Must-Try Product: Glossier Balm Dotcom ($16) – a multipurpose lip and skin salve in fun flavors.
5. SkinCeuticals
SkinCeuticals is a leader in science-backed skincare, especially for anti-aging and sun protection. Their vitamin C serums, like C E Ferulic, are dermatologist-recommended for brightening and protecting skin from free radicals. While pricier, their products are formulated in high-end labs for maximum efficacy.
Must-Try Product: SkinCeuticals C E Ferulic ($182) – a gold-standard antioxidant serum for radiant skin.
6. La Mer
La Mer is the epitome of luxury skincare, famous for its Miracle Broth—a blend of sea kelp, vitamins, and minerals. Founded by physicist Dr. Max Huber to heal his skin, the brand’s Crème de la Mer is a celebrity favorite for its deeply hydrating and restorative properties.
Must-Try Product: Crème de la Mer ($200 for 1 oz) – a rich, iconic moisturizer for ultimate hydration.

7. Paula’s Choice
Paula’s Choice, founded by skincare expert Paula Begoun, is all about transparency and science. Their 2% BHA Liquid Exfoliant is a holy grail for unclogging pores and smoothing skin texture. The brand’s detailed ingredient breakdowns help you make informed choices for your skin.
Must-Try Product: Skin Perfecting 2% BHA Liquid Exfoliant ($42) – fights blackheads and refines pores.
8. Dr. Dennis Gross Skincare
Dr. Dennis Gross Skincare blends clinical-grade ingredients with at-home convenience. Their Alpha Beta Universal Daily Peel is a game-changer for brighter, smoother skin. The brand also offers innovative devices, like the DrX SpectraLite FaceWare Pro, for professional-level results.
Must-Try Product: Alpha Beta Universal Daily Peel ($88 for 30 treatments) – a two-step peel for instant glow.
9. Mario Badescu
Mario Badescu has been a skincare staple since 1967, offering affordable products with a spa-like feel. Their Facial Spray with Aloe, Herbs, and Rosewater is a Gen Z favorite, perfect for refreshing and hydrating skin on the go.
Must-Try Product: Facial Spray with Aloe, Herbs, and Rosewater ($7) – a budget-friendly mist for all-day hydration.
10. Sunday Riley
Sunday Riley combines advanced science with natural botanicals for high-performance skincare. Their Good Genes Lactic Acid Treatment is a bestseller for exfoliating and brightening dull skin. The brand’s sleek packaging and effective formulas make it a favorite among beauty editors.
Must-Try Product: Good Genes All-In-One Lactic Acid Treatment ($85) – evens skin tone and boosts radiance.
How to Choose the Right Skincare Brand for You
With so many options, picking the perfect brand can feel daunting. Here are a few tips to help you decide:
- Know Your Skin Type: Are you oily, dry, combination, or sensitive? Brands like CeraVe and The Ordinary cater to all types, while La Mer is ideal for dry skin.
- Identify Your Concerns: Targeting acne? Try Paula’s Choice or Drunk Elephant. Want anti-aging? SkinCeuticals and Sunday Riley are great choices.
- Set a Budget: Affordable brands like The Ordinary and Mario Badescu deliver results without breaking the bank, while La Mer and SkinCeuticals are worth the splurge for luxury lovers.
- Check Ingredients: Look for science-backed ingredients like hyaluronic acid, retinol, vitamin C, or ceramides, which are staples in these brands’ formulas.
- Read Reviews: Customer feedback and dermatologist recommendations (like those for CeraVe and SkinCeuticals) can guide your choice.
Why These Brands Stand Out
These 10 brands were chosen for their innovation, quality, and popularity. Many, like CeraVe and The Ordinary, are backed by dermatologists and loved by Gen Z for their affordability and efficacy. Others, like La Mer and Drunk Elephant, are celebrated for their luxurious textures and clean beauty ethos. Whether you’re a skincare newbie or a seasoned pro, these American brands offer products that fit into any routine.
Where to Shop These Brands
You can find these skincare brands at major retailers like:
- Ulta: Stocks Glossier, Mario Badescu, and The Ordinary.
- Sephora: Carries Drunk Elephant, Sunday Riley, and La Mer.
- Amazon: Offers CeraVe, Paula’s Choice, and The Ordinary at competitive prices.
- Nordstrom: Perfect for high-end picks like SkinCeuticals and La Mer.
- Brand Websites: Shop directly for exclusive deals and sets.
Final Thoughts
Skincare is personal, and the right brand can make all the difference. From CeraVe’s budget-friendly staples to La Mer’s lavish creams, these 10 American skincare brands offer something for everyone. Try their hero products, experiment with new routines, and enjoy the glow-up. Your skin will thank you!
Which brand are you excited to try? Let us know in the comments, and share your favorite skincare tips!
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